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| Catalog Number | Size | Price |
|---|---|---|
| LS-C188733-0.25 | 0.25 mg (1 mg/ml) | $545 |
Monoclonal Rat anti‑Mouse ITGAM / CD11b Antibody (clone 5C6, IHC, IF) LS‑C188733
Monoclonal Rat anti‑Mouse ITGAM / CD11b Antibody (clone 5C6, IHC, IF) LS‑C188733
Note: This antibody replaces LS-C188735
Antibody:
ITGAM / CD11b Rat anti-Mouse Monoclonal (5C6) Antibody
Application:
IHC-Fr, IF, IP, Flo
Reactivity:
Mouse
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
ITGAM / CD11b Rat anti-Mouse Monoclonal (5C6) Antibody
Application:
IHC-Fr, IF, IP, Flo
Reactivity:
Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
CD11b antibody LS-C188733 is an unconjugated rat monoclonal antibody to mouse CD11b (ITGAM). Validated for Flow, IF, IHC and IP.
Target
Mouse ITGAM / CD11b
Synonyms
ITGAM | Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain
Host
Rat
Reactivity
Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG2b
Monoclonal
Clone
5C6
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Thioglycollate-elicited Peritoneal Macrophages (TPM).
Specificity
Recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. The antibody immunoprecipitates a heterodimer of 165 and 95kD. Clone 5C6 exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.
Applications
- IHC - Frozen
- Immunofluorescence
- Immunoprecipitation
- Flow Cytometry (1:100)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ITGAM / CD11b
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Mouse, Human, Rabbit
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Immunofluorescence, Immunoprecipitation, Flow Cytometry
Species:
Mouse, Human, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Dog, Bovine, Cat, Goat, Pig, Mustelid
Applications:
IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
