Human IL17A

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

M237

Unconjugated

Protein A purified

Preservative Free

Recombinant Human IL17 / IL17a protein

Human IL17. Has cross-reactivity with Canine IL17A. No cross-reactivity with mIL17A in ELISA assay

• ELISA (1 µg/ml)
• Blocking (0.5 µg/ml)
• Neutralization (50 ng/ml)

Block: In a functional ELISA which immobilized recombinant Human IL17a at 1ug/ml (100 µL/well) in the plate, the Rabbit anti-Human IL17a Monoclonal Antibody can block the binding of 0.5ug/ml of biotinylated recombinant Human IL17Ra to human IL17a, the EC50 is 0.60 ug/ml. Neutralization: The neutralization activity of IL17a Neutralizing Antibody is measured by its ability to neutralize IL6 secretion induced by human IL17a in the HFF human foreskin fibroblast. The Neutralization Titer (IC50) is typically 0.23-0.94 µg/mL in the presence of 50 ng/mL Recombinant Human IL17a. Please Note: Optimal concentrations/dilutions should be determined by the end user.

0.2 µm filtered solution in PBS

Store at 2°C to 8°C for up to 1 month. Aliquot and store at -20°C to -80°C for up to 1 year. Avoid freeze/thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q16552 NCBI: NM_002190 NP_002181.1