Target
Human IL12RB1 / CD212
Synonyms
IL12RB1 | CD212 | IL-12R subunit beta-1 | IL-12R-beta-1 | IL12R | Interleukin-12 receptor | IL-12 receptor subunit beta-1 | IL-12R-BETA1 | IL-12RB1 | CD212 antigen | IL-12 receptor beta component | IL12RB
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Horseradish Peroxidase.
Also available
Unconjugated or conjugated with
Biotin,
FITC.
Immunogen
Recombinant Human Interleukin-12 receptor subunit beta-1 protein (119-280AA)
Specificity
Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.