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Catalog Number Size Price
LS-B12387-50 50 µl (1 mg/ml) $460 
TDP-43 / TARDBP Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
TDP-43 / TARDBP Antibody - TDP-43 / TARDBP antibody was used to stain a section of formalin fixed adult rat brain, specifically the hippocampus. Hippocampal neuron nuclei are stained strongly. Chicken antibody to GFAP CPCA-GFAP (green) shows the processes of astrocytic glial cells. Nuclei of all cells are revealed with DAPI DNA stain (blue). The TARDP antibody stains neuronal nuclei strongly and the nuclei of some non-neuronal cells much more weakly. Neuronal nuclei therefore look crimson, since they are both red due to the content of TDP43 and blue due to their content of DNA, stained blue with DAPI.
TDP-43 / TARDBP Antibody - Blots of TDP-43 / TARDBP antibody on crude extract of mouse brain nuclear fraction (left lane) and cytoplasmic fraction (right lane) blotted with monoclonal antibody TDP-43 / TARDBP antibody. There is a strong clear band in the nuclear preparation running at 43kDa, and a much more minor band in the cytoplasmic fraction.
TDP-43 / TARDBP Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
TDP-43 / TARDBP Antibody - TDP-43 / TARDBP antibody was used to stain a section of formalin fixed adult rat brain, specifically the hippocampus. Hippocampal neuron nuclei are stained strongly. Chicken antibody to GFAP CPCA-GFAP (green) shows the processes of astrocytic glial cells. Nuclei of all cells are revealed with DAPI DNA stain (blue). The TARDP antibody stains neuronal nuclei strongly and the nuclei of some non-neuronal cells much more weakly. Neuronal nuclei therefore look crimson, since they are both red due to the content of TDP43 and blue due to their content of DNA, stained blue with DAPI.
TDP-43 / TARDBP Antibody - Blots of TDP-43 / TARDBP antibody on crude extract of mouse brain nuclear fraction (left lane) and cytoplasmic fraction (right lane) blotted with monoclonal antibody TDP-43 / TARDBP antibody. There is a strong clear band in the nuclear preparation running at 43kDa, and a much more minor band in the cytoplasmic fraction.
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IHC‑plus™ Monoclonal Mouse anti‑Human TDP‑43 / TARDBP Antibody (clone 3H8, IHC, IF, WB) LS‑B12387

IHC‑plus™ Monoclonal Mouse anti‑Human TDP‑43 / TARDBP Antibody (clone 3H8, IHC, IF, WB) LS‑B12387

Note: This antibody replaces LS-C204584
Antibody:
TDP-43 / TARDBP Mouse anti-Human Monoclonal (3H8) Antibody
Application:
IHC, IHC-P, IF, WB
Reactivity:
Human, Mouse, Rat, Bovine, Pig
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B12387-50
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
TDP-43 / TARDBP Mouse anti-Human Monoclonal (3H8) Antibody
Application:
IHC, IHC-P, IF, WB
Reactivity:
Human, Mouse, Rat, Bovine, Pig
Format:
Unconjugated, Unmodified

Specifications

Description
TARDBP antibody LS-B12387 is an unconjugated mouse monoclonal antibody to TARDBP (TDP-43) from human. It is reactive with human, mouse, rat and other species. Validated for IF, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Target
Human TDP-43 / TARDBP
Synonyms
TARDBP | ALS10 | TAR DNA-binding protein-43 | TDP-43 | TAR DNA binding protein | TAR DNA-binding protein 43 | TDP43
Host
Mouse
Reactivity
Human, Mouse, Rat, Bovine, Pig (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
3H8
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Full length recombinant human TDP43 expressed in and purified from E. coli.
Specificity
Clone 3H8 is known to react with TDP43 from human, cow, pig, mouse, rat and other mammals. Since the TDP43 protein sequence is highly conserved across species barriers, it is likely that the antibody is effective on many other species also.
Applications
  • IHC
  • IHC - Paraffin (1:50)
  • Immunofluorescence (1:1000)
  • Western blot (1:5000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Try at dilutions of 1:1000 and higher for immunofluorescence, 1:5000 and lower for western blotting.
Presentation
PBS, 0.05% Sodium Azide
Storage
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TDP-43 / TARDBP
Q13148 NM_007375 NP_031401.1

Validation

TDP-43 / TARDBP Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

IHC-plus™ TDP-43 / TARDBP Antibody (clone 3H8) for IHC, IF/Immunofluorescence, WB/Western LS-B12387 has an LSBio Rating of
Laboratory Validation Score (4)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/25/2024