Human GAPDH

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

4G5

Unconjugated

Protein A purified from ascites

Unmodified

Human cardiac muscle GADPH.

Recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyze the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin.

• IHC
• IHC - Paraffin (5 - 10 µg/ml)
• IHC - Frozen
• Immunofluorescence
• Western blot
• Immunoprecipitation
• ELISA

PBS, less than 0.1% Sodium Azide

Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P04406 NCBI: NM_002046 NP_002037.2