Mouse HAVCR2 / TIM-3

Rat

Mouse (tested or 100% immunogen sequence identity)

IgG2a,k Monoclonal

25F.1D6

FITC

Purified

Unmodified

Murine T cell clone AE7 cells.

Anti-mouse Tim-3 (T cell immunoglobulin domain, mucin domain 3) monoclonal antibody reacts with mouse Tim-3. This 281 amino acid type 1 transmembrane protein contains an immunoglobulin and mucin-like domain in its extra-cellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. Tim-3 is a member of the immunoglobulin super-family and is expressed on Th1 lymphocytes and CD11b+ macrophages. Tim-3 is a T helper type 1 (TH1)-specific molecule that regulates TH1 mediated auto and alloimmune responses and the induction of peripheral immunological tolerance. This antibody has been reported to work in Flow Cytometry and Immunohistochemistry. This FITC conjugated format is especially useful for direct flow cytometry.

• IHC
• Flow Cytometry (1 µg/10E6 cells)

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

PBS, 0.02% Sodium Azide, BSA

Short term: store at 4°C. Long term: aliquot and store -20°C. Avoid freeze-thaw cycles. Protect from light. Store undiluted.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q8TDQ0 NCBI: NM_032782 NP_116171.3