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Catalog Number Size Price
LS-C498828-50 50 µg $294 
LS-C498828-100 100 µg $360 
Antibody

Polyclonal Rabbit anti‑Human ERN1 / IRE1 Antibody (Biotin) LS‑C498828

Polyclonal Rabbit anti‑Human ERN1 / IRE1 Antibody (Biotin) LS‑C498828

Antibody:
ERN1 / IRE1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Biotin, Unmodified
Other formats:
Price
Catalog Number
$294
LS-C498828-50
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
ERN1 / IRE1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Biotin, Unmodified
Other formats:

Specifications

Description
IRE1 antibody LS-C498828 is a biotin-conjugated rabbit polyclonal antibody to human IRE1 (ERN1). Validated for ELISA.
Target
Human ERN1 / IRE1
Synonyms
ERN1 | ER to nucleus signalling 1 | Inositol-requiring enzyme 1 | Inositol-requiring protein 1 | Ire1-alpha | IRE1a | HIRE1p | IRE1 | Inositol-requiring 1 | IRE1P
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC, HRP.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Serine/threonine-protein kinase/endoribonuclease IRE1 protein (493-561AA)
Specificity
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Applications
  • ELISA
  • Applications tested for the base form of this product only
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ERN1 / IRE1
O75460 NM_001433 NP_001424.3

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 3/15/2025