Target
Human ERBB3 / HER3
Synonyms
ERBB3 | C-erbB-3 | C-erbB3 | ErbB-3 | HER3 | p85-sErbB3 | p45-sErbB3 | MDA-BF-1 | ErbB3-S | LCCS2 | p180-ErbB3
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Allophycocyanin.
Also available
Unconjugated or conjugated with
Biotin,
FITC,
HRP,
PE.
Immunogen
Extracellular fragment of recombinant human c-erbB-3/HER-3 oncoprotein. MW of Antigen: 185 kDa . Epitope: Extracellular domain. Cellular Localization: Cytoplasmic and cell membrane
Specificity
Does not block the binding of heregulin to c-erbB-31, has no effect on tyrosine kinase activity1, receptor internalization1, or tumorigenic growth of cells overexpressing the cerbB- 32. It is particularly well suited for immunoprecipitation of unoccupied as well as the occupied receptor1. Species cross-reactivity: human.