Target
Human EPHA2 / EPH Receptor A2
Synonyms
EPHA2 | CTPA | EPH receptor A2 | Ephrin type-A receptor 2 | Epithelial cell kinase | ECK | Sek-2 | ARCC2 | Soluble EPHA2 variant 1 | CTPP1
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG,k
Recombinant Monoclonal
Conjugations
Unconjugated
Purification
Protein A purified
Immunogen
1C1 was isolated after screening of a non-immunized human Fab phage library. Selection was based on the ability to bind soluble human recombinant EphA2 (aa 183-510). The Fab was subsequently converted to full length human IgG1.
Epitope
Human Ephrin Type A receptor 2
Specificity
1C1 binds specifically to the amino-termianal LBD (ligand-binding domain) region of the EphA2 ectodomain (IgG1 KD ~0.8 nM; Fab KD ~140 nM) and not to other related human Eph receptors such as EphA1, EphA2, and EphA4, or any EphB receptor family members.
Applications
- Immunofluorescence
- Western blot
- Flow Cytometry
- ELISA
- Agonist
Usage
Applications should be user optimized.
Presentation
PBS, 0.02% ProClin™ 300.
Storage
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About EPHA2 / EPH Receptor A2