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| Catalog Number | Size | Price |
|---|---|---|
| LS-B1986-50 | 50 µg (0.5 mg/ml) | $460 |
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2 of 2
IHC‑plus™ Monoclonal Mouse anti‑Human CXCR4 Antibody (clone 12G5, IHC, IF) LS‑B1986
IHC‑plus™ Monoclonal Mouse anti‑Human CXCR4 Antibody (clone 12G5, IHC, IF) LS‑B1986
Note: This antibody replaces LS-C41092
Antibody:
CXCR4 Mouse anti-Human Monoclonal (12G5) Antibody
Application:
IHC, IHC-P, IHC-Fr, IF, Flo
Reactivity:
Human, Chimpanzee, Baboon, African green monkey, Cynomolgus monkey, Rhesus monkey, Sooty Mangabey
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
CXCR4 Mouse anti-Human Monoclonal (12G5) Antibody
Application:
IHC, IHC-P, IHC-Fr, IF, Flo
Reactivity:
Human, Chimpanzee, Baboon, African green monkey, Cynomolgus monkey, Rhesus monkey, Sooty Mangabey
Format:
Unconjugated, Unmodified
Specifications
Description
CXCR4 antibody LS-B1986 is an unconjugated mouse monoclonal antibody to CXCR4 from human. It is reactive with human, african green monkey, baboon and other species. Validated for Flow, IF and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Target
Human CXCR4
Synonyms
CXCR4 | CD184 | CD184 antigen | Cmkar4 | Cxc chemokine receptor 4 | CXCR-4 | CXC-R4 | D2S201E | FB22 | Fusin | HM89 | LCR1 | NPY3R | NPYRL | NPYY3R | Npyy3 | HSY3RR | SDF-1 receptor | WHIM | C-x-c chemokine receptor 4 | LESTR | Neuropeptide Y receptor Y3 | NPYR
Host
Mouse
Reactivity
Human, Chimpanzee, Baboon, African green monkey, Cynomolgus monkey, Rhesus monkey, Sooty Mangabey
(tested or 100% immunogen sequence identity)
Clonality
IgG2a,k
Monoclonal
Clone
12G5
Conjugations
Unconjugated
Purification
Purified from tissue culture supernatant by affinity chromatography.
Modifications
Unmodified
Immunogen
CP-MAC-infected Sup-T1 cells
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- IHC - Frozen
- Immunofluorescence
- Flow Cytometry
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B1986 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1986 was determined to be 10 ug/ml.
Presentation
PBS, pH 7.2, 0.09% Sodium Azide
Storage
Store undiluted at 4°C. Avoid freezing.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CXCR4
Validation
Anti-CXCR4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-CXCR4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ CXCR4 Antibody (clone 12G5) for IHC, IF/Immunofluorescence, Flow LS-B1986 has an LSBio Rating of
Publications (4.1)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (2)
Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling. Thompson BD, Jin Y, Wu KH, Colvin RA, Luster AD, Birnbaumer L, Wu MX. The Journal of biological chemistry. 2007 282:9547-55.
Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Isnardi I, Ng YS, Menard L, Meyers G, Saadoun D, Srdanovic I, Samuels J, Berman J, Buckner JH, Cunningham-Rundles C, Meffre E. Blood. 2010 115:5026-36.
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Hamster, Rabbit, Chicken
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Species:
Mouse, Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
