Mouse CXCR4

Goat

Mouse (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Affinity purified

Unmodified

Synthetic peptide YSEEVGSGDYDSNKEPCFRDENVHFNR corresponding to aa14-40 within the N-Terminus of mouse CD184. Percent identity by BLAST analysis: Mouse (100%); Rat (93%); Baboon, Monkey, Marmoset, Elephant, Rabbit (81%).

aa14-40

Recognizes an epitope within the N-terminal (NT) region of mouse CD184, otherwise known as CXCR4 (C-X-C chemokine receptor type 4), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, ubiquitously expressed in blood and tissue cells, which acts as a specific receptor for the chemokine SDF-1 (Stromal cell-derived factor 1). Interaction of CD184 with SDF-1 mediates the chemotaxis of progenitor and mature blood cells, and is critical for B-lymphopoiesis and myelopoiesis. CD184 is a major co-receptor for infection by T-cell tropic strains of HIV1, and also a primary receptor for some HIV2 isolates. Is reported as being suitable for use in immunocytochemistry on mouse spleen leucocytes.

• IHC
• IHC - Paraffin (1:300)
• Western blot (1:1000)
• ELISA (1:50000)

PBS, 0.1% Sodium Azide, 0.1% BSA

Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P61073 NCBI: NM_003467 NP_003458.1