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| Catalog Number | Size | Price |
|---|---|---|
| LS-B2308-50 | 50 µg (0.25 mg/ml) | $485 |
IHC‑plus™ Polyclonal Rabbit anti‑Human CDH11 / Cadherin 11 Antibody (Intracellular, IHC, WB) LS‑B2308
IHC‑plus™ Polyclonal Rabbit anti‑Human CDH11 / Cadherin 11 Antibody (Intracellular, IHC, WB) LS‑B2308
Note: This antibody replaces LS-C4286
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Specifications
Description
Cadherin 11 antibody LS-B2308 is an unconjugated rabbit polyclonal antibody to Cadherin 11 (CDH11) (Intracellular) from human. It is reactive with human and mouse. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Target
Human CDH11 / Cadherin 11
Synonyms
CDH11 | CAD11 | Cadherin 11 | Cadherin-11 | CDHOB | OSF-4 | Osteoblast cadherin | OB | OB-cadherin | Ventral neural cadherin | Vnc
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Recombinant protein derived from the intracellular domain of the human Cadherin 11 protein.
Epitope
Intracellular
Specificity
Recognizes human Cadherin 11 at ~110kD. An additional band at ~130kD (presumably the Cadherin 11 precursor) may also be observed. Some crossreactivity with other Cadherins is observed in approximately the following order: Cadherin11>>R-Cadherin>Cadherin 8>>N-Cadherin=P-Cadherin. No crossreactivity with Cadherin 6 or E-Cadherin has been observed.
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- IHC - Frozen
- Western blot (1 - 2 µg/ml)
- ELISA (0.1 - 1 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B2308 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2308 was determined to be 5 ug/ml. Positive control: MDA. MB231 cells (human) and mouse L fibroblast lysates.
Presentation
PBS, pH 7.4, 0.09% Sodium Azide
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CDH11 / Cadherin 11
Validation
Anti-CDH11 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-CDH11 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ CDH11 / Cadherin 11 Antibody (Intracellular) for IHC, WB/Western, ELISA LS-B2308 has an LSBio Rating of
Publications (4.2)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (3)
Constitutive Activation of Integrin a9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis. Emori T, Hirose J, Ise K, Yomoda JI, Kasahara M, Shinkuma T, Yoshitomi H, Ito H, Hashimoto M, Sugahara S, Fujita H, Yamamoto N, Morita Y, Narumiya S, Aramori I,. Journal of immunology (Baltimore, Md. : 1950). 2017 199:3427-3436. (WB; Human)
Role of JAK-STAT signaling in the pathogenic behavior of fibroblast-like synoviocytes in rheumatoid arthritis: Effect of the novel JAK inhibitor peficitinib. Takashi Emori, Michiko Kasahara, Shingo Sugahara, Motomu Hashimoto, Hiromu Ito, Shuh Narumiya, Yasuyuki Higashi, Yasutomo Fujii. European journal of pharmacology. 2020 September;882:173238.
AXL Is a Key Factor for Cell Plasticity and Promotes Metastasis in Pancreatic Cancer. Wenting Du, Natalie Z Phinney, Huocong Huang, Zhaoning Wang, Jill Westcott, Jason E Toombs, Yuqing Zhang, Muhammad S Beg, Thomas M Wilkie, James B Lorens, Rolf A Brekken. Molecular cancer research : MCR. 2021 August;19:1412-1421.
Customer Reviews (0)
Featured Products
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, ELISA
Species:
Human, Rat
Applications:
IHC, IHC - Frozen, ICC, Western blot
Species:
Human, Mouse
Applications:
Western blot, ELISA
Species:
Human, Mouse
Applications:
Western blot, ELISA
Reactivity:
Human
Range:
0.312-20 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 3/4/2025
Date Requested: 3/4/2025
