Target
Human CD79A / CD79 Alpha
Synonyms
CD79A | CD79a antigen | Ig-alpha | MB-1 | MB-1 membrane glycoprotein | Surface IgM-associated protein | MB1
Reactivity
Human
(tested or 100% immunogen sequence identity)
Immunogen
Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1
Specificity
Recognizes an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin