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Catalog Number Size Price
LS-C751477-100 100 µg (1 mg/ml) $574 
CD59 Antibody - Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with CD59 Rabbit Recombinant Monoclonal Antibody (MACIF/2867R).
CD59 Antibody - SDS-PAGE Analysis Purified CD59 Rabbit Recombinant Monoclonal Antibody (MACIF/2867R). Confirmation of Purity and Integrity of Antibody.
CD59 Antibody - Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with CD59 Rabbit Recombinant Monoclonal Antibody (MACIF/2867R).
CD59 Antibody - SDS-PAGE Analysis Purified CD59 Rabbit Recombinant Monoclonal Antibody (MACIF/2867R). Confirmation of Purity and Integrity of Antibody.
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Recombinant Monoclonal Rabbit anti‑Human CD59 Antibody (clone MACIF/2867R, Azide‑free,Carrier‑free, IHC) LS‑C751477

Recombinant Monoclonal Rabbit anti‑Human CD59 Antibody (clone MACIF/2867R, Azide‑free,Carrier‑free, IHC) LS‑C751477

Antibody:
CD59 Rabbit anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (MACIF/2867R) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Azide-free, Carrier-free
Other formats:
Price
Catalog Number
$574
LS-C751477-100
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
CD59 Rabbit anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (MACIF/2867R) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Azide-free, Carrier-free
Other formats:

Specifications

Description
CD59 antibody LS-C751477 is an unconjugated rabbit recombinant monoclonal antibody to human CD59. Validated for IHC.
Target
Human CD59
Synonyms
CD59 | 16.3A5 | 1F5 | 1F5 antigen | CD59 glycoprotein | EL32 | EJ16 | G344 | HRF-20 | MAC-IP | MACIF | Ly-6-like protein | MEM43 | MIRL | MEM43 antigen | MIN2 | MIN3 | MSK21 | p18-20 | Protectin | MAC-inhibitory protein | MIC11 | T cell-activating protein | CD59 antigen | EJ30 | HRF20 | Human leukocyte antigen MIC11 | Lymphocytic antigen CD59/MEM43 | MIN1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Non-Reactivity
Baboon, Horse
Clonality
IgG Recombinant Monoclonal
Clone
MACIF/2867R
Conjugations
Unconjugated
Purification
Purified
Modifications
Azide-free, Carrier-free. Also available Unmodified.
Immunogen
Recombinant full-length human CD59 protein. Antigen Molecular Weight: 20 kDa
Specificity
Reacts with human CD59, a 20 kDa glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein (Workshop VI; Code N-L036). CD59 regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 is widely distributed on cells in all tissues. It inhibits formation of MAC, thus protecting cells from complement-mediated lysis. The expression of CD59 on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobinuria (PNH). This MAb recognizes CD59 transfected cells. It is useful for study on GPI-anchored proteins, PNH and CD59 functions.
Applications
  • IHC - Paraffin (1 - 2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Functional Studies - Flow Cytometry (0.5-1 ug/million cells) - Immunofluorescence (0.5-1 ug/ml) - Optimal dilution for a specific application should be determined.
Presentation
10 mM PBS
Storage
Store at -20°C or -80°C upon receipt.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CD59
P13987 NM_000611 NP_000602.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 12/4/2024