Target
Human CD46
Synonyms
CD46 | AHUS2 | CD46 antigen | MCP | Measles virus receptor | TLX | MIC10 | TRA2.10 | Membrane cofactor protein
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
R. Phycoerythrin.
Also available
Unconjugated or conjugated with
FITC.
Purification
Protein A purified
Immunogen
HPB-ALL cell line.
Specificity
Recognizes the human CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP). CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilization.
Applications
- Flow Cytometry (1:1)
- Applications tested for the base form of this product only
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 or 100 ul whole blood. Method sheets are available on request.
Presentation
PBS, 0.09% Sodium Azide, 1% BSA
Reconstitution
Use 1 ml of sterile Distilled water.
Storage
Store at 4°C. Do not freeze. Store untiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee