Mouse CD36

Rat

Mouse (tested or 100% immunogen sequence identity)

IgG2a Monoclonal

MF3

Unconjugated

Protein G purified

Low Endotoxin. Also available Unmodified.

IL-4 treated murine thioglycollate-elicited peritoneal macrophages.

Recognizes mouse CD36, an 85kD transmembrane glycoprotein which is primarily expressed on platelets, monocytes/macrophages, smooth muscle and endothelial cells. The CD36 molecule is type B scavenger receptor, which binds to multiple ligands including thrombospondin, anionic phospholipids, oxidized low density lipoproteins and long chain fatty acids. CD36 has diverse functions and is reported to play a role in innate immunity, platelet adhesion/aggregation and long chain fatty acid transport. The CD36 molecule also directly mediates cytoadhesion of erythrocytes infected with Plasmodium falciparum, and may be involved in the development of atherosclerotic lesions and the formation of foam cells. Antibodies produced by clone MF3 have been shown to inhibit IL-4 induced thioglycollate-elicited peritoneal macrophage fusion and significantly block IL-4/GM-CSF-induced bone-marrow derived macrophage fusion.

• Immunofluorescence
• Flow Cytometry

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

PBS

Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P16671 NCBI: NM_000072 NP_000063.2