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| Catalog Number | Size | Price |
|---|---|---|
| LS-C746930-20 | 20 µl (1.66 mg/ml) | $275 |
| LS-C746930-100 | 100 µl | $389 |
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Polyclonal Rabbit anti‑Human CD274 / B7‑H1 / PD‑L1 Antibody (IHC, IF, WB) LS‑C746930
Polyclonal Rabbit anti‑Human CD274 / B7‑H1 / PD‑L1 Antibody (IHC, IF, WB) LS‑C746930
Antibody:
CD274 / B7-H1 / PD-L1 Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IF, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
CD274 / B7-H1 / PD-L1 Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IF, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
PD-L1 antibody LS-C746930 is an unconjugated rabbit polyclonal antibody to PD-L1 (CD274 / B7-H1) from human. It is reactive with human, mouse and rat. Validated for IF, IHC and WB. Cited in 2 publications.
Target
Human CD274 / B7-H1 / PD-L1
Synonyms
CD274 | B7-H | B7 homolog 1 | B7-H1 | B7H1 | CD274 molecule | CD274 antigen | PDCD1 ligand 1 | PDL1 | PD-L1 | PDCD1L1 | PDCD1LG1 | Programmed death ligand 1
Host
Rabbit
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 19-238 of human CD274 (NP_054862.1). FTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNER
Applications
- IHC (1:50 - 1:200)
- Immunofluorescence (1:20 - 1:100)
- Western blot (1:500 - 1:2000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
The predicted MW is 20kDa/33kDa, while the observed MW by Western blot was 45kDa.
Presentation
PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CD274 / B7-H1 / PD-L1
LSBio Ratings
CD274 / B7-H1 / PD-L1 Antibody for IHC, IF/Immunofluorescence, WB/Western LS-C746930 has an LSBio Rating of
Publications (4.1)
Learn more about The LSBio Ratings Algorithm
Publications (2)
anlotinib alters tumor immune microenvironment by downregulating PD-L1 expression on vascular endothelial cells. Shaochuan Liu , Tingting Qin , Zhujun Liu, Jing Wang, Yanan Jia, Yingfang Feng, Yuan Gao, Kai Li. Cell death & disease. 2020 May;11:309.
The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer. William A Freed-Pastor, Laurens J Lambert, Zackery A Ely, Nimisha B Pattada, Arjun Bhutkar, George Eng, Kim L Mercer, Ana P Garcia, Lin Lin, William M Rideout rd, William L Hwang, Jason M Schenkel, Alex M Jaeger, Roderick T Bronson, Peter M K Westcott, Tyler D Hether, Prajan Divakar, Jason W Reeves, Vikram Deshpande, Toni Delorey, Devan Phillips, Omer H Yilmaz, Aviv Regev, Tyler Jacks. Cancer cell. 2021 October;39:1342-1360.e14.
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Flow Cytometry
Species:
Human
Applications:
Flow Cytometry, ELISA
Species:
Human
Applications:
Flow Cytometry, ELISA
Species:
Human
Applications:
Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Mouse
Applications:
IHC, IHC - Frozen, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
