Target
Human CBFA1 / RUNX2
Synonyms
RUNX2 | AML3 | CCD | CCD1 | OSF2 | PEBP2A1 | PEBP2A2 | PEA2-alpha A | PEBP2-alpha A | OSF-2 | PEBP2A | PEBP2aA1 | CBF-alpha-1 | CBFA1 | Oncogene AML-3 | PEA2aA | PEBP2aA
Reactivity
Human, Monkey, Mouse, Bat, Bovine, Dog, Hamster, Horse, Pig, Chicken
(tested or 100% immunogen sequence identity)
Predicted
Rat (at least 90% immunogen sequence identity)
Immunogen
A synthetic peptide (NPQGQSQITDPRQAQS) corresponding to amino acids 264-279 of human RUNX2 was used as immunogen for this antibody. RUNX2 and RUNX1 share an approximate 66% homology in peptide sequence used as immunogen. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Pig, Opossum, Turkey, Sparrow, Chicken (100%); Rat, Platypus, Lizard (94%); Xenopus, Medaka, Pufferfish, Zebrafish, Stickleback (88%).
Specificity
A portion of amino acids 250-300 of human RUNX2 RUNX2 and RUNX1 share an approximate 66% homology in peptide sequence used as immunogen.