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| Catalog Number | Size | Price |
|---|---|---|
| LS-C389475-7 | 7 ml | $574 |
1 of 2
2 of 2
Monoclonal Mouse anti‑Human BCL2 / Bcl‑2 Antibody (clone 8C8, Ready‑to‑Use, aa41‑54, IHC, IF, WB) LS‑C389475
Monoclonal Mouse anti‑Human BCL2 / Bcl‑2 Antibody (clone 8C8, Ready‑to‑Use, aa41‑54, IHC, IF, WB) LS‑C389475
Antibody:
BCL2 / Bcl-2 Mouse anti-Human Monoclonal (aa41-54) (Ready-to-Use) (8C8) Antibody
Application:
IHC, IHC-P, IF, WB, IP, Flo, ELISA
Reactivity:
Human, Chimpanzee, Monkey, Dog, Pig
Format:
Unconjugated, Ready-to-Use
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
BCL2 / Bcl-2 Mouse anti-Human Monoclonal (aa41-54) (Ready-to-Use) (8C8) Antibody
Application:
IHC, IHC-P, IF, WB, IP, Flo, ELISA
Reactivity:
Human, Chimpanzee, Monkey, Dog, Pig
Format:
Unconjugated, Ready-to-Use
Other formats:
Specifications
Description
Bcl-2 antibody LS-C389475 is an unconjugated mouse monoclonal antibody to Bcl-2 (BCL2) (aa41-54) from human. It is reactive with human, chimpanzee, dog and other species. Validated for ELISA, Flow, IF, IHC, IP and WB.
Target
Human BCL2 / Bcl-2
Synonyms
BCL2 | Apoptosis regulator Bcl-2 | B-cell CLL/lymphoma 2 | B-cell lymphoma protein 2 | Bcl-2 | PPP1R50
Host
Mouse
Reactivity
Human, Chimpanzee, Monkey, Dog, Pig
(tested or 100% immunogen sequence identity)
Non-Reactivity
Mouse, Rat
Clonality
IgG1,k
Monoclonal
Clone
8C8
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Ready-to-Use.
Also available Unmodified or Azide-free, BSA-free.
Immunogen
A synthetic peptide, aa 41-54 (G aa PAPGIFSSQPG-Cys) of human Bcl-2 protein. Percent identity by BLAST analysis: Human, Chimpanzee, Cat, Pig, Dog (100%); Gorilla, Orangutan, Bovine, Goat (91%); Galago (82%).
Epitope
aa41-54
Specificity
Human BCL2 / Bcl-2
Applications
- IHC
- IHC - Paraffin (1:1)
- Immunofluorescence
- Western blot
- Immunoprecipitation
- Flow Cytometry
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 alpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative. ELISA: Order BSA-free format for coating.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About BCL2 / Bcl-2
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Mouse, Rat
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Species:
Human
Applications:
Immunoprecipitation
Species:
Human, Monkey, Dog, Pig
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Species:
Human, Mouse, Rat, Dog
Applications:
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/21/2024
Date Requested: 11/21/2024
