Target
Human BAFF / TNFSF13B
Synonyms
TNFSF13B | B-cell-activating factor | BAFF | ApoL related ligand TALL-1 | B-lymphocyte stimulator | CD257 | BLYS | Delta4 BAFF | Delta BAFF | TALL-1 | TALL1 | ZTNF4 | THANK | B lymphocyte stimulator | CD257 antigen | TNFSF20
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Conjugations
FITC.
Also available conjugated with
AP,
Biotin,
HRP,
PE.
Purification
Ion exchange chromatography
Immunogen
Peptide corresponding to amino acids 254-269 of human BLyS.
Specificity
Recognizes BLyS (also known as BAFF, TALL-1 and THANK), a novel member of the tumor necrosis factor (TNF) superfamily. BLyS (B lymphocyte stimulator) and its receptor TACI/BCMA are involved in the development of autoimmune diseases. BlyS has been shown to activate NFkB and JNK (c-jun N-terminal kinase) and induce apoptosis. Species cross-reactivity: mouse, human, rat.