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| Catalog Number | Size | Price |
|---|---|---|
| LS-C74520-100 | 100 µg | $941 |
Monoclonal Mouse anti‑Human BACE1 / BACE Antibody (WB) LS‑C74520
Monoclonal Mouse anti‑Human BACE1 / BACE Antibody (WB) LS‑C74520
Antibody:
BACE1 / BACE Mouse anti-Human Monoclonal Antibody
Application:
WB, IP, ELISA, Neut
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
BACE1 / BACE Mouse anti-Human Monoclonal Antibody
Application:
WB, IP, ELISA, Neut
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
BACE antibody LS-C74520 is an unconjugated mouse monoclonal antibody to BACE (BACE1) from human. It is reactive with human and mouse. Validated for ELISA, IP, Neut and WB.
Target
Human BACE1 / BACE
Synonyms
BACE1 | APP beta-secretase | Asp 2 | ASP2 | Aspartyl protease 2 | Aspartylprotease 2 | Beta-secretase | Beta-site APP-cleaving enzyme | BACE | HSPC104 | KIAA1149 | B-Secretase | Beta-secretase 1 | Memapsin-2
Host
Mouse
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
NS0-derived rhBACE-1 ectodomain.
Specificity
Recognizes human BACE-1 ectodomain. Species cross-reactivity: Mouse.
Applications
- Western blot
- Immunoprecipitation
- ELISA
- Neutralization
Usage
Suitable for use in ELISA, Immunoprecipitation/ Western Blot and Neutralization. The enzyme was then assayed with a peptide substrate. 50% of the proteolytic activity was inhibited by the antibody at 10 ug/ml (IC50) under conditions in which the enzyme was present at 10 ug/ml and the substrate concentration was 10uM. Considering the molecular masses of the enzyme (75kD) and the antibody (150kD), IC50 was achieved at ~0.5:1 molar ratio of the antibody to the enzyme. Did not inhibit rhCathepsin D activity under the same conditions.
Presentation
Lyophilized PBS, pH 7.4, 5% Trehalose
Reconstitution
Reconstitute in sterile PBS.
Storage
Lyophilized and resuspended forms: store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About BACE1 / BACE
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Rat
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
