Target
Human ATG4A
Synonyms
ATG4A | AUTL2 | Autophagin-2 | APG4A | Autophagin 2 | Cysteine protease ATG4A | HAPG4A | APG4 autophagy 4 homolog A
Reactivity
Human
(tested or 100% immunogen sequence identity)
Immunogen
KLH conjugated synthetic peptide corresponding to amino acids 100-114 of human ATG4A. The corresponding sequence differs by 2 amino acids in mouse and rat.
Specificity
Recognizes human ATG4A (Autophagy-related protein 4 homolog A), otherwise known as APG4A/Cysteine protease ATG4A, a cytosolic cysteine protease and member of the peptidase C54 family, predominantly expressed in skeletal muscle and brain, which plays a central role in the cleavage of the C-Terminal region of the target proteins GABARAPL2, MAP1LC3 or GABARAP during autophagy.(AHP2220) has been shown to be suitable for use in immunoprecipitation using HEK-293T cell lysates.