Target
Human AQP3 / Aquaporin 3
Synonyms
AQP3 | Aquaporin 3 (GIL blood group) | Aquaglyceroporin-3 | AQP-3 | Aquaporin 3 | Aquaporin 3 (Gill blood group) | Aquaporin-3 | GIL
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Horseradish Peroxidase.
Also available
Unconjugated or conjugated with
FITC,
Biotin.
Immunogen
Recombinant human Aquaporin-3 protein (210-244AA)
Specificity
Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism (By similarity).