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SELP / P-Selectin / CD62P

selectin P (granule membrane protein 140kDa, antigen CD62)

SELP encodes a 140 kD protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.

Gene Name: selectin P (granule membrane protein 140kDa, antigen CD62)
Synonyms: SELP, CD62P, CD62, GMP-140, GMRP, Granule membrane protein 140, LECAM3, P-selectin, PSEL, CD62P antigen, GMP140, Granulocyte membrane protein, GRMP, PADGEM
Target Sequences: NM_003005 NP_002996.2

Publications (3)

1
Targeting P-selectin blocks neuroblastoma growth. Nolo R, Herbrich S, Rao A, Zweidler-McKay P, Kannan S, Gopalakrishnan V, ,. Oncotarget. 2017 8:86657-86670. (IP; Human) [Full Text Article] [PubMed:29156825] Related Antibodies: LS-B3656.
2
Chronic Embolic Pulmonary Hypertension Caused by Pulmonary Embolism and Vascular Endothelial Growth Factor Inhibition. Neto-Neves EM, Brown MB, Zaretskaia MV, Rezania S, Goodwill AG, McCarthy BP, Persohn SA, Territo PR, Kline JA. The American journal of pathology. 2017 April;187:700-712. [Full Text Article] [PubMed:28183533] [PMC:PMC5397717]
3
Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer. Marcus Ruscetti, John P Morris th, Riccardo Mezzadra, James Russell, Josef Leibold, Paul B Romesser, Janelle Simon, Amanda Kulick, Yu-Jui Ho, Myles Fennell, Jinyang Li, Robert J Norgard, John E Wilkinson, Direna Alonso-Curbelo, Ramya Sridharan, Daniel A Heller, Elisa de Stanchina, Ben Z Stanger, Charles J Sherr, Scott W Lowe. Cell. 2020 April;181:424-441.e21. [Full Text Article] [PubMed:32234521] [PMC:PMC7278897]

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Antibodies (103)
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SELP / P-Selectin / CD62P (164)
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SELP / P-Selectin / CD62P Antibody - Anti-CD62P antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
SELP / P-Selectin / CD62P Mouse anti-Human Monoclonal (Psel.KO.2.5) Antibody
Human
Flo, IHC, IHC-P, IP
Unconjugated
0.05 mg/$460
SELP / P-Selectin / CD62P Antibody - ABCG2 antibody, PB9364, IHC-paraffin: Human Lung Cancer Tissue.
Select
SELP / P-Selectin / CD62P Rabbit anti-Human Polyclonal (aa42-271) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
SELP / P-Selectin / CD62P Mouse anti-Human Monoclonal (PE) Antibody
Pig, Human
Flo, IP
PE Conjugated
100 µl/$951
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SELP / P-Selectin / CD62P Mouse anti-Human Monoclonal (RPE) (Psel.KO.2.12) Antibody
Human
Flo
RPE Conjugated
100 Tests/$485
SELP / P-Selectin / CD62P Antibody - Flow cytometry of thrombin activated human peripheral blood platelets with Mouse anti-Human CD62P:RPE This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SELP / P-Selectin / CD62P Mouse anti-Human Monoclonal (RPE) (Psel.KO.2.5) Antibody
Human
Flo
RPE Conjugated
100 Tests/$485
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$779
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$741
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$582
SELP / P-Selectin / CD62P Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
SELP / P-Selectin / CD62P Rabbit anti-Human Polyclonal (81-130 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Select
SELP / P-Selectin / CD62P Mouse anti-Human Monoclonal (RPE) (Psel.KO.2.7) Antibody
Human
Flo
RPE Conjugated
100 Tests/$485
SELP / P-Selectin / CD62P Antibody - Western Blot; Sample: Recombinant SELP, Human.
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SELP / P-Selectin / CD62P Rabbit anti-Human Polyclonal (aa58-195) Antibody
Human
WB
Unconjugated
100 µl/$272; 200 µl/$299; 500 µl/$387; 1 ml/$431; 2 ml/$519; 5 ml/$870
SELP / P-Selectin / CD62P Antibody - Western blot analysis of CD62P expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.
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SELP / P-Selectin / CD62P Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Mouse, Sheep, Bovine, Rat, Human
WB
Unconjugated
100 µl/$299
SELP / P-Selectin / CD62P Antibody - Human Tonsil, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SELP / P-Selectin / CD62P Mouse anti-Human Monoclonal (AK-6) Antibody
Human
Flo, IF, IHC-Fr, IHC-P, WB
Unconjugated
0.05 mg/$460
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.041 - 30 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
Select
SELP / P-Selectin / CD62P Rabbit anti-Mouse Monoclonal (Preservative Free) (001) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
100 µl/$412
SELP / P-Selectin / CD62P Antibody - Western blot - Anti-CD62P Picoband antibody
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SELP / P-Selectin / CD62P Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, Flo, ICC, IHC, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
SELP / P-Selectin / CD62P Mouse anti-Human Monoclonal (Low Endotoxin) (AK4) Antibody
Human, Non-Human Primates
Flo, Func, ICC, IP, WB
Unconjugated, Low Endotoxin
0.1 mg/$302
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SELP / P-Selectin / CD62P Mouse anti-Human Monoclonal (Psel.KO.2.12) Antibody
Human
Flo, IHC, IHC-Fr, IP
Unconjugated
25 µg/$281; 0.2 mg/$471
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
SELP / P-Selectin / CD62P ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rabbit
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Saliva, Serum, Tissue Homogenates, Urine
1 Plate/$925
Select
SELP / P-Selectin / CD62P Mouse anti-Human Monoclonal (Psel.KO.2.7) Antibody
Human
Flo, IHC-Fr, IP
Unconjugated
25 µg/$281; 0.2 mg/$471
SELP / P-Selectin / CD62P Antibody - Immunohistochemistry of paraffin-embedded human esophagus using SELP antibody (40x lens).
Select
SELP / P-Selectin / CD62P Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
SELP / P-Selectin / CD62P Antibody - Western blot of recombinant SELP / P-Selectin / CD62P.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SELP / P-Selectin / CD62P Rabbit anti-Mouse Polyclonal (aa58-259) Antibody
Mouse
WB
Unconjugated
100 µl/$270; 200 µl/$295; 500 µl/$380; 1 ml/$423; 2 ml/$507; 5 ml/$845
SELP / P-Selectin / CD62P Antibody - 5-10ug/ml, non-reducing and non-heating conditions.
Select
SELP / P-Selectin / CD62P Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, IHC-Fr, WB
Unconjugated
100 µg/$632
Viewing 1-25 of 164 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).