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PXN / Paxillin
paxillin
PXN / Paxillin is a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).
| Gene Name: | paxillin |
| Synonyms: | PXN, Paxillin |
| Target Sequences: | NM_002859 NP_002850.2 P49023 |
Publications (3)
1
RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility. Yao H, Dashner EJ, van Golen CM, van Golen KL. Oncogene. 2006 25:2285-96.
[PubMed:16314838]
2
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin. Schmalzigaug R, Garron ML, Roseman JT, Xing Y, Davidson CE, Arold ST, Premont RT. Cellular signalling. 2007 19:1733-44. (ICC, IP)
[PubMed:17467235]
[PMC:PMC2025689]
3
Podosomes are present in a postsynaptic apparatus and participate in its maturation. Proszynski TJ, Gingras J, Valdez G, Krzewski K, Sanes JR. Proceedings of the National Academy of Sciences of the United States of America. 2009 106:18373-8.
[PubMed:19822767]
[PMC:PMC2775295]
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Antibodies
(128)
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(20)
Proteins
(17)
Type
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(1)
Cell-Based Phosphorylation
(2)
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(5)
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(1)
Over-Expression Lysate
(7)
Primary
(128)
Recombinant
(9)
Sandwich
(11)
Sandwich CLIA
(1)
Target
PXN / Paxillin
(165)
Reactivity
Human
(134)
Mouse
(69)
Rat
(57)
Bat
(1)
Bovine
(11)
Chicken
(19)
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(3)
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(2)
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(3)
Guinea pig
(1)
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(3)
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(9)
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(3)
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(4)
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(27)
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(123)
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(31)
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(13)
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(11)
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rabbit
(99)
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(28)
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(1)
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IgG
(49)
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(22)
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(2)
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(3)
IgG2b
(1)
Clonality
monoclonal mc
(26)
polyclonal pc
(100)
recombinant monoclonal rmc
(2)
Clone
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(1)
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(1)
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(1)
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(2)
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(2)
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(2)
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(2)
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(2)
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(3)
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(1)
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(5)
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(14)
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(3)
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(5)
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(7)
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(7)
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(7)
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(5)
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(1)
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(89)
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pTyr118
(10)
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(9)
aa201-461
(8)
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(8)
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(8)
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(7)
C-Terminus
(4)
aa111-160
(4)
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(4)
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(3)
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(3)
120-200 aa
(2)
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(2)
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(2)
aa1-50
(2)
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(2)
10-90 aa
(1)
210-290 aa
(1)
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(1)
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(1)
Leu25
(1)
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(1)
aa123-172
(1)
aa144-193
(1)
aa15-64
(1)
aa217-266
(1)
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(1)
aa33-82
(1)
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(1)
p118
(1)
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(1)
p272
(1)
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(1)
pSer126
(1)
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(1)
pSer272
(1)
Publications
No
(165)
Sample Type
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(3)
Cell Lysates
(1)
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(5)
Serum
(5)
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(3)
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6His, N-terminus
(3)
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(3)
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(1)
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(3)
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(7)
Species
Human
(12)
Mouse
(1)
Rat
(1)
Source
293T Cells
(3)
E. coli
(5)
HEK 293 Cells
(6)
Wheat Germ Extract
(3)
Purification
Purified
(3)
PXN / Paxillin Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PXN / Paxillin Rabbit anti-Human Polyclonal (pSer178) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
PXN / Paxillin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
PXN / Paxillin Rabbit anti-Human Polyclonal (aa456-472) Antibody
Chicken, Sheep, Bovine, Rat, Pig, Horse, Bat, Rabbit, Mouse, Guinea pig, Human, Monkey
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
PXN / Paxillin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
PXN / Paxillin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
PXN / Paxillin Mouse anti-Chicken Monoclonal Antibody
Chicken, Mouse, Dog, Rat, Human
ELISA, ICC, IHC, IP, WB
Unconjugated
100 µg/$1,022
PXN / Paxillin Rabbit anti-Human Polyclonal (Leu25) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
PXN / Paxillin Mouse anti-Human Monoclonal Antibody
Chicken, Bovine, Mouse, Rat, Human
ELISA, ICC, IP, WB
Unconjugated
250 µg/$854
E. coli
6His, N-terminus
63 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 250 µg/$518
PXN / Paxillin Rabbit anti-Human Polyclonal (aa15-64) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PXN / Paxillin Rabbit anti-Human Polyclonal (pTyr118) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µl/$689
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
PXN / Paxillin Rabbit anti-Human Polyclonal (10-90 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PXN / Paxillin Rabbit anti-Human Polyclonal (pTyr88) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PXN / Paxillin Rabbit anti-Human Polyclonal (p31) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PXN / Paxillin Rabbit anti-Human Polyclonal (p118) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PXN / Paxillin Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
PXN / Paxillin Mouse anti-Human Monoclonal (aa59-274) Antibody
Human
ICC, WB
Unconjugated
100 µg/$884
PXN / Paxillin Mouse anti-Human Monoclonal (pTyr31) (1D4B) Antibody
Human
ICC, WB
Unconjugated
100 µg/$872
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of 165
product results
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