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| Catalog Number | Size | Price |
|---|---|---|
| LS-B2010-50 | 50 µg (0.5 mg/ml) | $440 |
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2 of 2
IHC‑plus™ Polyclonal Rabbit anti‑Human ALK2 / ACVR1 Antibody (aa496‑509, IHC, WB) LS‑B2010
IHC‑plus™ Polyclonal Rabbit anti‑Human ALK2 / ACVR1 Antibody (aa496‑509, IHC, WB) LS‑B2010
Note: This antibody replaces LS-C19345, LS-C63637
Antibody:
ALK2 / ACVR1 Rabbit anti-Human Polyclonal (aa496-509) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Xenopus
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
ALK2 / ACVR1 Rabbit anti-Human Polyclonal (aa496-509) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Xenopus
Format:
Unconjugated, Unmodified
Specifications
Description
ACVR1 antibody LS-B2010 is an unconjugated rabbit polyclonal antibody to ACVR1 (ALK2) (aa496-509) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Target
Human ALK2 / ACVR1
Synonyms
ACVR1 | Activin A receptor type I | Activin A receptor, type I | ACTR-I | ActRIA | ACVR1A | ALK2 | Activin receptor-like kinase 2 | Activin receptor type-1 | ACTRI | ACVRLK2 | ALK-2 | Activin receptor type I | Actr1 | FOP | Hydroxyalkyl-protein kinase | SKR1 | TSRI | TSR-I | Tsk7L
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Xenopus
(tested or 100% immunogen sequence identity)
Predicted
Chicken (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
A synthetic peptide corresponding to amino acids 496-509 (TKIDNSLDKLKTDC) of amino acids 475-525 of human ACVR1, GenBank NP 001096. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Xenopus (100%); Opossum, Turkey, Chicken, Platypus, Salmon (93%); Stickleback, Pufferfish (86%).
Epitope
aa496-509
Specificity
In human kidney, additional bands are seen at approximately 27 and 14 kD.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- Western blot (3 - 5 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B2010 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2010 was determined to be 10 ug/ml.
Presentation
PBS, 0.05% Sodium Azide, 0.2% Gelatin
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ALK2 / ACVR1
Validation
Anti-ACVR1 antibody IHC of human skeletal muscle, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-ACVR1 antibody IHC of human skeletal muscle, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ ALK2 / ACVR1 Antibody (aa496-509) for IHC, WB/Western LS-B2010 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (1)
Coco is a dual activity modulator of TGFß signaling. Deglincerti A, Haremaki T, Warmflash A, Sorre B, Brivanlou AH. Development (Cambridge, England). 2015 142:2678-85. (IP; Xenopus laevis)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, Western blot, Flow Cytometry, ELISA
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Mouse, Human
Applications:
IHC, IHC - Paraffin, Western blot
Source:
Human
Tag:
Myc-DDK (Flag)
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
