Human A2M / Alpha-2-Macroglobulin

Goat

Human (tested or 100% immunogen sequence identity)

Polyclonal

Unconjugated

Immunoaffinity absorbed

Unmodified

Human alpha-2 macroglobulin

Human A2M / Alpha-2-Macroglobulin. The reactivity of the antiserum is restricted to human alpha-2 macroglobulin. In immunoelectro- phoresis and radial immunodiffusion, using various antiserum concentrations against normal human plasma a single precipitin line is obtained which shows a reaction of identity with the precipitin line obtained with purified alpha-2 macroglobulin. No reaction is obtained with any other plasma protein components or serum. Cross-reactivity The antiserum does not cross-react with any other component of human plasma. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. Cross-reactivity of this antiserum has been tested in double radial immunodiffusion against several ser of other species with the following results: bovine + dog t cat + goat - monkey ++ mouse - rat - rabbit +.

• Immunodiffusion

This product is intended for use in precipitating techniques as immunoelectrophoresis and single or double radial immunodiffusion (Mancini, Ouchterlony) to identify the presence of alpha-2 macroglobulin in human plasma or other body fluids or to determine its concentration. This antiserum is not intended for use in non-precipitating antibody binding or other highly sensitive assays, but this does exclude such use if proper controls are included.

Lyophilized antiserum

Use 1 ml of sterile Distilled water.

Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P01023 NCBI: NM_000014 NP_000005.2