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ZWINT is a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Name: | ZW10 interacting kinetochore protein |
Synonyms: | ZWINT, HZwint-1, KNTC2AP, Zwint-1, ZW10 interactor, ZWINT1, ZW10-interacting protein 1 |
Target Sequences: | NM_007057 NP_008988.2 O95229 |
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