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Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells.
Gene Name: | zinc finger and SCAN domain containing 4 |
Synonyms: | ZSCAN4, Zinc finger protein 494, ZNF494 |
Target Sequences: | AI138628 |
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