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ZSCAN4

zinc finger and SCAN domain containing 4

Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells.

Gene Name: zinc finger and SCAN domain containing 4
Synonyms: ZSCAN4, Zinc finger protein 494, ZNF494
Target Sequences: AI138628

Publications (2)

1
Zscan4 interacts directly with human Rap1 in cancer cells regardless of telomerase status. Lee K, Gollahon LS. Cancer biology & therapy. 2014 15:1094-105. (WB; Human) [Full Text Article] [PubMed:24840609] [PMC:PMC4119077] Related Antibodies: LS-B5074.
2
SMCHD1 terminates the first embryonic genome activation event in mouse two-cell embryos and contributes to a transcriptionally repressive state. Meghan L Ruebel, Kailey A Vincent, Peter Z Schall, Kai Wang, Keith E Latham. American journal of physiology. Cell physiology. 2019 Oct;317:C655-C664. [Full Text Article] [PubMed:31365290] [PMC:PMC6850993] Related Antibodies: LS-B5074.

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
ZSCAN4 (5)
No (5)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
ZSCAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
48.8 kDa
20 µg/$150
ZSCAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
48.8 kDa
100 µg/$494
ZSCAN4 Protein - 12.5% SDS-PAGE of human ZSCAN4 stained with Coomassie Blue
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Wheat Germ Extract
GST
75.4 kDa
10 µg/$479; 25 µg/$670
ZSCAN4 Protein - Purified recombinant protein ZSCAN4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
48.8 kDa
20 µg/$1,107
ZSCAN4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).