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Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP.
Gene Name: | solute carrier family 30 (zinc transporter), member 5 |
Family/Subfamily: | Transporter , Cation Diffusion Facilitator |
Synonyms: | SLC30A5, HZTL1, ZNT5, Zinc transporter ZTL1, ZTL1, ZnT-5, ZnT-like transporter 1, ZNTL1, Zinc transporter 5 |
Target Sequences: | NM_022902 NP_075053.2 Q8TAD4 |
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