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ZNF280B

zinc finger protein 280B

ZNF280B is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding.

Gene Name: zinc finger protein 280B
Family/Subfamily: Zinc Finger
Synonyms: ZNF280B, 5OY11.1, 5'OY11.1, SUHW2, Zinc finger protein 279, ZNF632, Zinc finger protein 632, D87009.C22.3, Zinc finger protein 280B, ZNF279
Target Sequences: Q86YH2 Q86YH2

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Products
Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
ZNF280B (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
ZNF280B Protein - 12.5% SDS-PAGE of human SUHW2 stained with Coomassie Blue
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Wheat Germ Extract
GST
87.9 kDa
2 µg/$439
ZNF280B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
61.4 kDa
20 µg/$150
ZNF280B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
61.4 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).