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ZMYM3 is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation. Several alternatively spliced transcript variants have been found for this gene.
Gene Name: | zinc finger, MYM-type 3 |
Synonyms: | ZMYM3, DXS6673E, KIAA0385, MYM, Zinc finger protein 261, ZNF261, Zinc finger MYM-type protein 3, Zinc finger, MYM-type 3, XFIM, ZNF198L2 |
Target Sequences: | NM_005096 NP_005087.1 Q14202 |
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