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The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.
Gene Name: | zinc finger with KRAB and SCAN domains 1 |
Synonyms: | ZKSCAN1, ZNF139, ZNF36, ZSCAN33, Zinc finger protein 36, KOX18, PHZ-37, Zinc finger protein 139, Zinc finger protein KOX18 |
Target Sequences: | U09848 AAC50264.1 P17029 |
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