ZIC2

Zic family member 2

Acts as a transcriptional activator or repressor. Plays important roles in the early stage of organogenesis of the CNS. Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets. Its transcriptional activity is repressed by MDFIC. Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline. Drives the expression of EPHB1 on ipsilaterally projecting growth cones. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'. Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

ZIC2 (3)

Publications

No (3)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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Human ZIC2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71368

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.8 kDa

Price:

20 µg/$1,107

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Human ZIC2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89601

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.8 kDa

Price:

20 µg/$215

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ZIC2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114840

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.8 kDa

Price:

100 µg/$710

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