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ZFP91 is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2.
Gene Name: | ZFP91 zinc finger protein |
Synonyms: | ZFP91, DMS-8, DSM-8, FKSG11, Zinc finger protein 757, Zinc finger protein 91 homolog, ZFP-91, ZNF757, Penta zinc finger protein, PZF, ZFP91 zinc finger protein |
Target Sequences: | AX026141 IPI00074745.1 Q96JP5 |
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