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ZAK / MLTK

sterile alpha motif and leucine zipper containing kinase AZK

ZAK is a MLK(MAP3K) type protein kinase that mediates the cell cycle signals leading to G2 arrest, possibly by regulating cyclin E expression. ZAK is activated in response to osmotic shock with hyperosmolar media through autophosphorylation. The expression of ZAK is increased by activation of the ERK/MAPK pathway and activates the ERK, JNK/SAPK, p38, and ERK5 pathways. There are two alternatively spliced forms of ZAK, and only the alpha form causes the disruption of actin stress fibers and dramatic morphological changes.

Gene Name: sterile alpha motif and leucine zipper containing kinase AZK
Family/Subfamily: Protein Kinase , MLK(MAP3K)
Synonyms: ZAK, HCCS-4, MLTK, MLK-related kinase, MLK7, MLT, MRK, Mlklak, AZK, Mixed lineage kinase 7, PK
Target Sequences: AB049733 NP_057737.2 Q9NYL2

☰ Filters
Products
Proteins (10)
Over-Expression Lysate (6)
Recombinant (4)
ZAK / MLTK (10)
No (10)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (8)
Human (7)
293T Cells (3)
HEK 293 Cells (5)
Wheat Germ Extract (2)
Purified (1)
ZAK / MLTK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
91 kDa
20 µg/$215
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293T Cells
Myc-DDK (Flag)
91 kDa
20 µg/$215
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293T Cells
Myc-DDK (Flag)
51.4 kDa
20 µg/$150
ZAK / MLTK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
51.4 kDa
100 µg/$494
ZAK / MLTK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
91 kDa
100 µg/$710
ZAK / MLTK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
91 kDa
100 µg/$710
ZAK / MLTK Protein - 12.5% SDS-PAGE of human ZAK stained with Coomassie Blue
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Wheat Germ Extract
GST
75.79 kDa
10 µg/$479; 25 µg/$670
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HEK 293 Cells
Myc-DDK (Flag)
91 kDa
20 µg/$1,107
Select
HEK 293 Cells
Myc-DDK (Flag)
51.4 kDa
20 µg/$1,107
ZAK / MLTK Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Viewing 1-10 of 10 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).