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Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. Requires to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1). Seems to act in the processing of OPA1.
Gene Name: | YME1-like 1 ATPase |
Family/Subfamily: | Protease , Cysteine C39 |
Synonyms: | YME1L1, FTSH, FTSH1, Meg-4, YME1 (S.cerevisiae)-like 1, YME1-like 1 (S. cerevisiae), YME1-like protein 1, MEG4, PAMP, YME1L |
Target Sequences: | NM_014263 NP_055078.1 Q96TA2 |
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