YBX1 / YB1

Y box binding protein 1

Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors By similarity. Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

YBX1 / YB1 (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (1)

His (2)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Mouse (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (2)

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Human YBX1 / YB1 Protein (Recombinant His) - LS-G3076

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Mouse YBX1 / YB1 Protein (Recombinant His) (Full Length) - LS-G23195

Source:

Yeast

Tag:

His

Molecular Weight:

37.6 kD

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Human YBX1 / YB1 Protein (Recombinant GST) (Full Length) - LS-G29548

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

62.3 kDa

Price:

2 µg/$439

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Human YBX1 / YB1 Protein (Recombinant GST, N-terminus) (aa51-139) - LS-G59449

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human YBX1 / YB1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85592

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.7 kDa

Price:

20 µg/$150

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Human YBX1 / YB1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69808

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.7 kDa

Price:

20 µg/$1,107

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YBX1 / YB1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116564

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.7 kDa

Price:

100 µg/$494

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Human YBX1 / YB1 Protein (Recombinant His, N-Terminal) (Gln134-Glu324) - LS-G132681

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

26/36kDa

Price:

10 µg/$255; 50 µg/$322; 200 µg/$560; 100 µg/$447; 1 mg/$1,476; 500 µg/$1,092; 5 mg/$2,390; 2 mg/$1,641

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