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Infectious Disease
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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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YBX1 / YB1
Y box binding protein 1
Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors By similarity. Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro.
| Gene Name: | Y box binding protein 1 |
| Synonyms: | YBX1, CBF-A, DBPB, CSDB, DNA-binding protein B, MDR-NF1, NSEP-1, NSEP1, Y box binding protein 1, Y-box transcription factor, Y-box-binding protein 1, YB-1, BP-8, CSDA2, EFI-A, Enhancer factor I subunit A, YB1 |
| Target Sequences: | NM_004559 NP_004550.2 P67809 |
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YBX1 / YB1
(56)
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(18)
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(4)
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(6)
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(1)
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(2)
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YBX1 / YB1 Mouse anti-Human Monoclonal (4F12) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
YBX1 / YB1 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
YBX1 / YB1 Rabbit anti-Human Polyclonal (aa143-192) (HRP) Antibody
Xenopus, Rat, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
YBX1 / YB1 Rabbit anti-Human Polyclonal (aa143-192) (Biotin) Antibody
Xenopus, Rat, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
YBX1 / YB1 Rabbit anti-Human Polyclonal (aa143-192) (FITC) Antibody
Xenopus, Rat, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
YBX1 / YB1 Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
YBX1 / YB1 Rabbit anti-Human Polyclonal (aa224-274) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
YBX1 / YB1 Rabbit anti-Human Polyclonal (aa293-320) Antibody
Mouse, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
YBX1 / YB1 Mouse anti-Human Monoclonal (OTI11A7) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
YBX1 / YB1 Mouse anti-Human Monoclonal (Carrier-free) (OTI11A7) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
YBX1 / YB1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$688
YBX1 / YB1 Rabbit anti-Human Polyclonal (aa274-324) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
YBX1 / YB1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$575
YBX1 / YB1 Mouse anti-Human Monoclonal (OTI7B4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
YBX1 / YB1 Mouse anti-Human Monoclonal (Carrier-free) (OTI7B4) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Yeast
His
37.6 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
YBX1 / YB1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, WB
Unconjugated, Preservative Free
100 µl/$412
YBX1 / YB1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
YBX1 / YB1 Rabbit anti-Human Polyclonal (aa276-305) Antibody
Human
IF, WB
Unconjugated
400 µl/$393
YBX1 / YB1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
YBX1 / YB1 Rabbit anti-Human Polyclonal (aa149-178) Antibody
Human
IF, WB
Unconjugated
400 µl/$393
YBX1 / YB1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
YBX1 / YB1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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