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XDH / Xanthine Oxidase
xanthine dehydrogenase
Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.
| Gene Name: | xanthine dehydrogenase |
| Synonyms: | XDH, Xanthene dehydrogenase, XOR, Xanthine dehydrogenase/oxidase, Xanthine oxidase, XO, Xanthine dehydrogenase, Xanthine oxidoreductase, XDHA |
| Target Sequences: | NM_000379 NP_000370.2 P47989 |
Publications (3)
1
Aging enhances pressure-induced arterial superoxide formation. Jacobson A, Yan C, Gao Q, Rincon-Skinner T, Rivera A, Edwards J, Huang A, Kaley G, Sun D. American journal of physiology. Heart and circulatory physiology. 2007 293:H1344-50.
[PubMed:17557915]
2
Role of xanthine oxidase activation and reduced glutathione depletion in rhinovirus induction of inflammation in respiratory epithelial cells. Papi A, Contoli M, Gasparini P, Bristot L, Edwards MR, Chicca M, Leis M, Ciaccia A, Caramori G, Johnston SL, Pinamonti S. The Journal of biological chemistry. 2008 283:28595-606. (WB; Human)
[Full Text Article]
[PubMed:18678861]
[PMC:PMC2661410]
3
Xanthine oxidase inhibition prevents atrial fibrillation in a canine model of atrial pacing-induced left ventricular dysfunction. Masao Sakabe, Akira Fujiki, Tamotsu Sakamoto, Yosuke Nakatani, Koichi Mizumaki, Hiroshi Inoue. Journal of cardiovascular electrophysiology. 2012 October;23:1130-5. [Full Text Article]
[PubMed:22587612]
Related Antibodies: LS-C59315.
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
XDH / Xanthine Oxidase Rabbit anti-Human Polyclonal (aa206-234) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
XDH / Xanthine Oxidase Rabbit anti-Human Polyclonal (aa206-234) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated
200 µl/$952
XDH / Xanthine Oxidase Rabbit anti-Human Polyclonal (aa206-234) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
XDH / Xanthine Oxidase Rabbit anti-Human Polyclonal (aa206-234) (FITC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
XDH / Xanthine Oxidase Rabbit anti-Human Polyclonal (aa206-234) (APC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
XDH / Xanthine Oxidase Rabbit anti-Human Polyclonal (aa206-234) (PE) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$748
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
XDH / Xanthine Oxidase Rabbit anti-Bovine Polyclonal Antibody
Bovine
ELISA, WB
Unconjugated
2 ml/$1,225
E. coli
His-GST
63.1 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
XDH / Xanthine Oxidase Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
XDH / Xanthine Oxidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
XDH / Xanthine Oxidase Rabbit anti-Bovine Polyclonal (Lyophilized) Antibody
Bovine
ELISA, IP, WB
Unconjugated, Lyophilized
100 µg/$567
XDH / Xanthine Oxidase Mouse anti-Human Monoclonal (aa1-280) (OTI5D8) Antibody
Human
WB
Unconjugated
100 µl/$434
XDH / Xanthine Oxidase Rabbit anti-Human Polyclonal (aa1-300) Antibody
Bovine, Pig, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
XDH / Xanthine Oxidase Rabbit anti-Human Polyclonal (aa206-234) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
XDH / Xanthine Oxidase Rabbit anti-Rat Polyclonal (aa415-464) (Biotin) Antibody
Rabbit, Mouse, Goat, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
XDH / Xanthine Oxidase Rabbit anti-Bovine Polyclonal (Biotin) Antibody
Bovine
ELISA, IF, IHC, WB
Biotin Conjugated
1 ml/$438
XDH / Xanthine Oxidase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
XDH / Xanthine Oxidase Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
10 µg/$318; 100 µg/$470
XDH / Xanthine Oxidase Rabbit anti-Bovine Polyclonal (Liquid) (Biotin) Antibody
Bovine
DB, ELISA, IP, WB
Biotin Conjugated, Liquid
25 µl/$304
XDH / Xanthine Oxidase Rabbit anti-Bovine Polyclonal (Lyophilized) (Biotin) Antibody
Bovine
DB, ELISA, IP, WB
Biotin Conjugated, Lyophilized
100 µg/$552
XDH / Xanthine Oxidase Rabbit anti-Bovine Polyclonal (HRP) Antibody
Bovine
ELISA, IHC, WB
HRP Conjugated
100 µg/$769
XDH / Xanthine Oxidase Rabbit anti-Bovine Polyclonal (Liquid) Antibody
Bovine
ELISA, IP, WB
Unconjugated, Liquid
25 µl/$304
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