WNT3

wingless-type MMTV integration site family, member 3

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

WNT3 (8)

Publications

No (8)

Tag

10His, N-terminus (1)

6His, N-terminus (1)

DDK,C-terminus (1)

GST (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Mouse (3)

Source

293T Cells (1)

CHO Cells (1)

E. coli (3)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (2)

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Mouse WNT3 Protein (Recombinant 6His, N-terminus) - LS-G23192

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

39.46 kD

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Human WNT3 Protein (Recombinant His-T7) (aa59-355) - LS-G26141

Source:

E. coli

Tag:

His-T7

Molecular Weight:

37.1 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human WNT3 Protein (Recombinant GST) (Full Length) - LS-G30900

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

66 kDa

Price:

2 µg/$439

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Human WNT3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91964

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.4 kDa

Price:

20 µg/$150

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WNT3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101966

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.4 kDa

Price:

100 µg/$494

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Human WNT3 Protein (Recombinant DDK,C-terminus) - LS-G145319

Source:

CHO Cells

Tag:

DDK,C-terminus

Molecular Weight:

37.4 kDa

Price:

20 µg/$1,111

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Mouse WNT3 Protein (Recombinant 10His, N-terminus) (Full Length) - LS-G137139

Source:

E. coli

Tag:

10His, N-terminus

Molecular Weight:

43.0 kDa

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Mouse WNT3 Protein (Recombinant His-SUMO) (aa22-355) - LS-G21324

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

53.44 kD

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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