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WNT3
wingless-type MMTV integration site family, member 3
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
| Gene Name: | wingless-type MMTV integration site family, member 3 |
| Family/Subfamily: | WNT , not assigned-WNT |
| Synonyms: | WNT3, Proto-oncogene Int-4 homolog, Proto-oncogene Wnt-3, INT4, WNT-3 proto-oncogene protein |
| Target Sequences: | NM_030753 NP_110380.1 P56703 |
Publications (2)
1
Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes. Kraushar ML, Viljetic B, Wijeratne HR, Thompson K, Jiao X, Pike JW, Medvedeva V, Groszer M, Kiledjian M, Hart RP, Rasin MR. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 35:10911-26. (WB; Human)
[Full Text Article]
[PubMed:26245956]
[PMC:PMC4524969]
Related Antibodies: LS-B3241.
2
Extrinsic Regulators of mRNA Translation in Developing Brain: Story of WNTs. Yongkyu Park, Midori Lofton, Diana Li, Mladen-Roko Rasin. Cells. 2021 Jan;10:253. [Full Text Article]
[PubMed:33525513]
[PMC:PMC7911671]
Related Antibodies: LS-C774904.
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WNT3 Goat anti-Human Polyclonal (aa315-329) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Mouse, Dog, Bovine, Bat, Rat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
WNT3 Mouse anti-Human Monoclonal (OTI1G7) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
WNT3 Mouse anti-Human Monoclonal (aa128-355) (Carrier-free) (OTI1G7) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
WNT3 Rabbit anti-Human Polyclonal (aa59-355) Antibody
Human
WB
Unconjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$597; 2 ml/$826; 5 ml/$1,352
WNT3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µg/$442
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$792
Sandwich
96-Well Strip Plate
Mouse
39.07 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$897
Yeast
6His, N-terminus
39.46 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
E. coli
His-T7
37.1 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
WNT3 Mouse anti-Human Monoclonal (aa128-355) (OTI1C5) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
WNT3 Mouse anti-Human Monoclonal (aa128-355) (Carrier-free) (OTI1C5) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
WNT3 Goat anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC-P, WB
Unconjugated
0.1 mg/$518
WNT3 Mouse anti-Human Monoclonal (aa128-355) (OTI3G5) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
WNT3 Mouse anti-Human Monoclonal (aa128-355) (Carrier-free) (OTI3G5) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
WNT3 Mouse anti-Human Monoclonal (OTI1F6) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
WNT3 Mouse anti-Human Monoclonal (aa128-355) (Carrier-free) (OTI1F6) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
WNT3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
WNT3 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
WNT3 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
WNT3 Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
WNT3 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
WNT3 Rabbit anti-Human Polyclonal (aa155-184) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
WNT3 Rabbit anti-Human Polyclonal (aa155-184) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
WNT3 Rabbit anti-Human Polyclonal (aa155-184) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
WNT3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
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