WISP3

WNT1 inducible signaling pathway protein 3

WISP3 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

WISP3 (5)

Publications

No (5)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (2)

Biologically Active

Biologically active (2)

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Human WISP3 Protein (Recombinant) - LS-G85

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

36.8 kDa

Price:

5 µg/$268; 20 µg/$349

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Human WISP3 Protein (Recombinant GST) (Full Length) - LS-G31356

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

67.8 kDa

Price:

2 µg/$439

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Human WISP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89214

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.1 kDa

Price:

20 µg/$150

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WISP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117034

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.1 kDa

Price:

100 µg/$494

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Human WISP3 Protein (Recombinant) - LS-G131450

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~37.1 kDa

Price:

5 µg/$291

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