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WDR36 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG).
Gene Name: | WD repeat domain 36 |
Synonyms: | WDR36, Glaucoma 1, open angle, G, GLC1G, UTP21, WD repeat domain 36, TA-WDRP, TAWDRP |
Target Sequences: | Q8NI36 Q8NI36 |
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