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WBP11 is a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.
Gene Name: | WW domain binding protein 11 |
Synonyms: | WBP11, Npw38-binding protein, SIPP1, SNP70, Npw38-binding protein NpwBP, NPWBP, WW domain binding protein 11, WW domain-binding protein 11, WBP-11 |
Target Sequences: | NM_016312 NP_057396.1 Q9Y2W2 |
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