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WASF3 is a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. A pseudogene of this gene have been defined on chromosome 6. Alternative splicing results in multiple transcript variants
Gene Name: | WAS protein family, member 3 |
Synonyms: | WASF3, Brush-1, KIAA0900, Protein WAVE-3, WAS protein family, member 3, WAVE3, SCAR3, WASP family protein member 3 |
Target Sequences: | NM_006646 NP_006637.2 Q9UPY6 |
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