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WAPAL / WAPL

wings apart-like homolog (Drosophila)

Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.

Gene Name: wings apart-like homolog (Drosophila)
Synonyms: WAPAL, Friend of EBNA2 protein, FOE, KIAA0261, WAPL
Target Sequences: D87450 NP_055860.1 Q7Z5K2

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Proteins (1)
Recombinant (1)
WAPAL / WAPL (1)
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Human (1)
Wheat Germ Extract (1)
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WAPAL / WAPL Protein - 12.5% SDS-PAGE of human KIAA0261 stained with Coomassie Blue
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Wheat Germ Extract
GST
69.96 kDa
10 µg/$479; 25 µg/$670
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).