VR1 / TRPV1

transient receptor potential cation channel, subfamily V, member 1

Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis (By similarity). Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca2+-dependent outward rectification, followed by a long-lasting refractory state. Mild extracellular acidic pH (6.5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions (pH <6) directly activate the channel.

☰ Filters

Products

ELISA Kits (11)

Type

Custom (3)

Sandwich (8)

Target

VR1 / TRPV1 (11)

Reactivity

Human (4)

Mouse (3)

Rat (3)

Dog (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (9)

Publications

No (11)

Sample Type

Cell Lysates (3)

Plasma (5)

Serum (5)

Tissue Homogenates (6)

Select

Human VR1 / TRPV1 (Sandwich ELISA) ELISA Kit - LS-F7693

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$730

Select

Human VR1 / TRPV1 (Sandwich ELISA) ELISA Kit - LS-F12857

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Mouse VR1 / TRPV1 (Sandwich ELISA) ELISA Kit - LS-F7453

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$748

Select

Rat VR1 / TRPV1 (Sandwich ELISA) ELISA Kit - LS-F36019

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Dog VR1 / TRPV1 (Custom ELISA) ELISA Kit - LS-F16463

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Mouse VR1 / TRPV1 (Custom ELISA) ELISA Kit - LS-F16464

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Rat VR1 / TRPV1 (Custom ELISA) ELISA Kit - LS-F16465

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Mouse VR1 / TRPV1 (Sandwich ELISA) ELISA Kit - LS-F38351

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human VR1 / TRPV1 (Sandwich ELISA) ELISA Kit - LS-F34144

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human VR1 / TRPV1 (Sandwich ELISA) ELISA Kit - LS-F52770

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$968

Select

Rat VR1 / TRPV1 (Sandwich ELISA) ELISA Kit - LS-F74522

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$646

Viewing 1-11 of 11 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: ELISA Kits

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.