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VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

VPS37A belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.

Gene Name: vacuolar protein sorting 37 homolog A (S. cerevisiae)
Synonyms: VPS37A, HCRP1, HVps37A, Vacuolar protein sorting 37A, ESCRT-I complex subunit VPS37A, PQBP2, SPG53
Target Sequences: AAH67754.1 Q8NEZ2

Publications (1)

1
MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation. Yoon S, Kovalenko A, Bogdanov K, Wallach D. Immunity. 2017 July;47:51-65. (Human) [Full Text Article] [PubMed:28666573]

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Antibodies (21)
Primary (21)
VPS37A (21)
Human (21)
Mouse (9)
Rat (8)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
IHC (5)
IHC-P (2)
WB (20)
ELISA (1)
ICC (1)
IF (4)
IP (2)
Peptide-ELISA (1)
rabbit (21)
Product Group
PathPlus Other (1)
IgG (12)
polyclonal pc (21)
APC (1)
APC Conjugated (1)
Biotin Conjugated (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (11)
N-Terminus (4)
aa1-50 (1)
aa200-250 (1)
No (21)
VPS37A Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
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VPS37A Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
VPS37A Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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VPS37A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC-P, WB
Unconjugated
50 µl/$460
VPS37A Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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VPS37A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
VPS37A Antibody - Western blot analysis of extracts of various cell lines, using VPS37A antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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VPS37A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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VPS37A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
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VPS37A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
VPS37A Antibody - Detection of human and mouse VPS37A by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-VPS37A antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
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VPS37A Rabbit anti-Human Polyclonal (aa200-250) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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VPS37A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
VPS37A Antibody - VPS37A antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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VPS37A Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
VPS37A Antibody - VPS37A antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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VPS37A Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
VPS37A Antibody - VPS37A antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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VPS37A Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
VPS37A Antibody - VPS37A antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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VPS37A Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
VPS37A Antibody
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VPS37A Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$597; 2 ml/$826; 5 ml/$1,352
VPS37A Antibody
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VPS37A Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$351; 200 µl/$411; 500 µl/$618; 1 ml/$774; 2 ml/$1,010; 5 ml/$1,757
VPS37A Antibody
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VPS37A Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$329; 200 µl/$381; 500 µl/$550; 1 ml/$654; 2 ml/$890; 5 ml/$1,487
VPS37A Antibody
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VPS37A Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$362; 200 µl/$427; 500 µl/$666; 1 ml/$826; 2 ml/$1,067; 5 ml/$1,892
VPS37A Antibody
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VPS37A Rabbit anti-Human Polyclonal (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703
VPS37A Antibody
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VPS37A Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703
VPS37A Antibody
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VPS37A Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703
VPS37A Antibody
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VPS37A Rabbit anti-Human Polyclonal (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$535; 200 µl/$714; 500 µl/$1,236; 1 ml/$1,545; 2 ml/$2,163; 5 ml/$4,053
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VPS37A Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).