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VEGFD

c-fos induced growth factor (vascular endothelial growth factor D)

Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

Gene Name: c-fos induced growth factor (vascular endothelial growth factor D)
Synonyms: FIGF, C-Fos-induced growth factor, VEGFD, VEGF-D
Target Sequences: NM_004469 NP_004460.1 O43915

Publications (2)

1
Implication of vascular endothelial growth factor A and C in revealing diagnostic lymphangiogenic markers in node-positive bladder cancer. Poyet C, Thomas L, Benoit TM, Delmo DA, Luberto L, Banzola I, Günthart MS, Sais G, Eberli D, Sulser T, Provenzano M. Oncotarget. 2017 March;8:21871-21883. [Full Text Article] [PubMed:28423532] [PMC:PMC5400630]
2
Mesenchymal Stromal Cells Inhibit Inflammatory Lymphangiogenesis in the Cornea by Suppressing Macrophage in a TSG-6-Dependent Manner. Song HB, Park SY, Ko JH, Park JW, Yoon CH, Kim DH, Kim JH, Kim MK, Lee RH, Prockop DJ, Oh JY. Molecular therapy : the journal of the American Society of Gene Therapy. 2018 January;26:162-172. [Full Text Article] [PubMed:29301108] [PMC:PMC5763076]

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Proteins (14)
Over-Expression Lysate (2)
Recombinant (12)
VEGFD (14)
No (14)
6His, C-terminus (4)
GST (2)
His (1)
His, N-Terminal (3)
Myc-DDK (Flag) (2)
Human (9)
Mouse (3)
Rat (1)
293F Cells (2)
293T Cells (1)
CHO Cells (1)
E. coli (3)
HEK 293 Cells (2)
Human Cells (2)
Mammalian Cells (2)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (6)
Biologically active (2)
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
12.18kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
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HEK 293 Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
26.2 kDa
2 µg/$268; 10 µg/$349
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E. coli
GST
40.5 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
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CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
18-19 kDa (SDS-PAGE)
50 µg/$478; 10 µg/$304; 1 mg/$2,653
VEGFD Protein - 12.5% SDS-PAGE of human FIGF stained with Coomassie Blue
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Wheat Germ Extract
GST
64.68 kDa
2 µg/$439
VEGFD Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
40.44 kDa
20 µg/$150
VEGFD Protein - Recombinant Vascular Endothelial Growth Factor D By SDS-PAGE
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E. coli
His
13.7 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
VEGFD Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
40.44 kDa
100 µg/$494
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293F Cells
His, N-Terminal
21kDa
10 µg/$321; 50 µg/$692; 200 µg/$1,284; 100 µg/$1,082; 1 mg/$2,544; 500 µg/$2,042; 5 mg/$4,831; 2 mg/$2,736
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293F Cells
His, N-Terminal
21kDa
10 µg/$347; 50 µg/$852; 200 µg/$1,493; 100 µg/$1,270; 1 mg/$2,803; 500 µg/$2,298; 5 mg/$5,951; 2 mg/$3,175
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
13.1kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
VEGFD Protein - Recombinant Vascular Endothelial Growth Factor D (VEGFD) by SDS-PAGE
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E. coli
His, N-Terminal
13.7kDa
10 µg/$288; 50 µg/$487; 200 µg/$972; 100 µg/$780; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
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Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
13.1 kDa
10 µg/$288; 50 µg/$436
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Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
12.2 kDa
10 µg/$288; 50 µg/$436
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).